This iconic Italian bitter liqueur features a rendering of an artichoke on its label, the edible thistle is only the most prominent name in an array of more than a dozen botanical ingredients that make this memorable liqueur. Traditionally served as an aperitif on its own or with soda, orange juice, or tonic, or sometimes as a digestivo. Recently, Cynar has been riding the wave of interest in bitter liqueurs among craft bartenders, and today it's enjoying a bit more prominence in the American bar. Mixed with rye whiskey and sweet vermouth instead of Campari for a twist on the classic Negroni. Cynar substitutes remarkably well for other bitter liqueurs in a number of cocktails, and others have been built around its complex flavor.